PUBLISHED WORK

[121]-Network pharmacology and molecular docking approaches to elucidate the potential compounds and targets of Saeng-Ji-Hwang-Ko for treatment of type 2 diabetes mellitus (2022)

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[120]-Coenzyme Q10 encapsulated in micelles ameliorates osteoarthritis by inhibiting inflammatory cell death (2022)

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[119]-Ethyl Gallate Dual-Targeting PTPN6 and PPARγ Shows Anti-Diabetic and Anti-Obese Effects (2022)

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[118]-Structure–Activity Relationship of Synthetic Ginkgolic Acid Analogs for Treating Type 2 Diabetes by PTPN9 Inhibition (2022)

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[117]-Site-Selective Antibody–Drug Conjugation by a Proximity-Driven S to N Acyl Transfer Reaction on a Therapeutic Antibody (2022)

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[116]-Terminalin from African Mango (Irvingia gabonensis) Stimulates Glucose Uptake through Inhibition of Protein Tyrosine Phosphatases (2022)

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[115]-Ethyl Gallate Dual-Targeting PTPN6 and PPARγ Shows Anti-Diabetic and Anti-Obese Effects (2022)

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[114]-Chebulinic Acid Suppresses Adipogenesis in 3T3-L1 Preadipocytes by Inhibiting PPP1CB Activity (2022)

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[113]-Nepetin Acts as a Multi‐Targeting Inhibitor of Protein Tyrosine Phosphatases Relevant to Insulin Resistance (2022)

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[112]-Linoleic acid exerts antidiabetic effects by inhibiting protein tyrosine phosphatases associated with insulin resistance (2021)

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[111]-Eco-friendly synthesis of SnO2-Cu nanocomposites and evaluation of their peroxidase mimetic activity (2021)

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[110]-A FRET‐Based Fluorescent Probe to Screen Anticancer Drugs, Inhibiting p73 Binding to MDM2 (2021)

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[109]-Protein tyrosine phosphatases (PTPs) in diabetes: causes and therapeutic opportunities (2021)

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[108]-Metabolite Profile of Cucurbitane-Type Triterpenoids of Bitter Melon (Fruit of Momordica charantia) and Their Inhibitory Activity against Protein Tyrosine Phosphatases Relevant to Insulin Resistance (2021)

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[107]-Phloridzin Acts as an Inhibitor of Protein-Tyrosine Phosphatase MEG2 Relevant to Insulin Resistance (2021)

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[106]-Polyphyllin D Shows Anticancer Effect through a Selective Inhibition of Src Homology Region 2-Containing Protein Tyrosine Phosphatase-2 (SHP2) (2021)

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[105]-Photoconjugation of an Fc-Specific Peptide Enables Efficient DAR 2 Antibody–Drug Conjugate Formation (2020)

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[104]-Identification of Vaccinia‐H1 Related Phosphatase as an Anticancer Target for 1,2,3,4,6‐O‐Pentagalloylglucose (2020)

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[103]-Reclamation of hexavalent chromium using catalytic activity of highly recyclable biogenic Pd (0) nanoparticles (2020)

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[102]-Phytosynthesis of palladium nanoclusters: an efficient nanozyme for ultrasensitive and selective detection of reactive oxygen species (2020)

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[101]-Enzyme mimetic activity of ZnO-Pd nanosheets synthesized via a green route (2020)

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[100]-Facile synthesis of triangular and hexagonal anionic gold nanoparticles and evaluation of their cytotoxicity (2019)

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[99]-Synthesis of Functionalized Silica Particles for Label‐free Detection of PTP1B Using FRET (2019)

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[98]-Chemical constituents of the root bark of Ulmus davidiana var. japonica and their potential biological activities (2019)

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[97]-Biogenic nanomaterials: Site-Selective C–H Alkylation of Diazine N-Oxides Enabled by Phosphonium Ylides (2019)

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[96]-Biogenic nanomaterials: Synthesis, characterization, growth mechanism, and biomedical applications (2019)

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[95]-Ginkgetin, a biflavone from Ginkgo biloba leaves, prevents adipogenesis through STAT5-mediated PPARγ and C/EBPα regulation (2019)

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[94]-Monitoring metal-amyloid-β complexation by a FRET-based probe: design, detection, and inhibitor screening (2019)

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[93]-Sesquiterpenes from Curcuma zedoaria rhizomes and their cytotoxicity against human gastric cancer AGS cells (2019)

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[92]-Fridamycin A, a Microbial Natural Product, Stimulates Glucose Uptake without Inducing Adipogenesis (2019)

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[91]-Identification of chebulinic acid as a dual targeting inhibitor of protein tyrosine phosphatases relevant to insulin resistance (2019)

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[90]-Metal-induced redshift of optical spectra of gold nanoparticles: An instant, sensitive, and selective visual detection of lead ions (2019)

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[89]-Recent Advances in pH-Sensitive Polymeric Nanoparticles for Smart Drug Delivery in Cancer Therapy (2018) 

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[88]-Ginkgolic acid as a dual-targeting inhibitor for protein tyrosine phosphatases relevant to insulin resistance, Bioorganic Chemistry (2018) 

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[87]-Label-free detection of protein tyrosine phosphatase 1B (PTP1B) using a rationally designed Forster resonance energy transfer (FRET) probe (2018) 

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[86]-Identification of sennoside A as a novel inhibitor of the slingshot (SSH) family proteins related to cancer metastasis (2017) 

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[85]-Intrinsic Forster resonance energy transfer imaging technique (iFIT) for detection of native protein in live cells (2016) 

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[84]-Mitochondria-Targeting Chromogenic and Fluorescence Turn-On Probe for the Selective Detection of Cysteine by Caged Oxazolidinoindocyanine (2016) 

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[83]-Cyclic peptide ligand with high binding capacity for affinity purification of immunoglobulin G (2016) 

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[82]-Development of Stable Non-Ionic Lipid Nanoparticles (2016) 

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[81]-Fc-binding ligands of immunoglobulin G: An overview of high affinity proteins and peptides (2016) 

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[80]-Homogeneous detection of caspase-3 using intrinsic fluorescence resonance energy transfer (iFRET) (2015) 

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[79]-Stimulation of angiogenesis and survival of endothelial cells by human monoclonal Tie2 receptor antibody (2015) 

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[78]-A lactate-induced response to hypoxia (2015) 

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[77]-IgG Fc-Binding Peptide (FcBP)-Tat Conjugate as a Smart Antibody Carrier into Live Cells (2015) 

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[76]-Phosphoprotein phosphatase 1CB (PPP1CB), a novel adipogenic activator, promotes 3T3-L1 adipogenesis (2015) 

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[75]-Functionalized Protein Nanocages as a Platform of Targeted Therapy and Immunodetection (2015) 

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[74]-Discovery of coumarin derivatives as acceptors for intrinsic fluorescence resonance energy transfer (iFRET) of proteins (2014) 

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[73]-ToF-SIMS analysis of diadenosine triphosphate and didadenosine tetraphosphate using bismuth and argon cluster ion beams (2014) 

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[72]-Intrinsic tryptophan fluorescence in the detection and analysis of proteins: a focus on Forster resonance energy transfer techniques (2014) 

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[71]-Structural basis for the dephosphorylating activity of PTPRQ towards phosphatidylinositide substrates (2013)

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[70]-Recent Advances in Target Characterization and Identification by Photoaffinity Probes (2013)

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[69]-Structural asymmetry of procaspase-7 bound to a specific inhibitor (2013)

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[68]-Chitosan-based intelligent theragnosis nanocomposites enable pH-sensitive drug release with MR-guided imaging for cancer therapy (2013) 

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[67]-Fabrication of nanoporous TiO2 hollow capsules using core-shell silica nanoparticle templates (2012)

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[66]-Glyceraldehyde-3-phosphate, a glycolytic intermediate, prevents cells from apoptosis by lowering s-nitrosylation of glyceraldehyde-3-phosphate dehydrogenase (2012)

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[65]-Identification of 3-acyl-2-phenylamino-1,4-dihydroquinolin-4-one derivatives as inhibitors of the phosphatase SerB653 in Porphyromonas gingivalis, implicated in periodontitis (2012)

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[64]-Color-Tunable Photoluminescent Fullerene Nanoparticles (2012)

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[63]-Molecular insight into the role of the leucine residue on the L2 loop in the catalytic activity of caspase-3 and -7 (2012)

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[62]-Developing an antibody-binding protein cage as a modular delivery nanoplatform (2012)

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[61]-A selective seoul-fluor-based bioprobe, sfbp, for vaccinia h1-related phosphatase?a dual-specific protein tyrosine phosphatase (2012)

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[60]-Acetylation of malate dehydrogenase 1 promotes adipogenic differentiation via activating its enzymatic activity (2012)

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[59]-Crystal structure of xenotropic murine leukaemia virus-related virus (XMRV) ribonuclease H (2012)

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[58]-A facile synthetic route to diazepinone derivatives via ring closing metathesis and its application for human cytidine deaminase inhibitors (2012)

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[57]-Recent Advances in Protein Tyrosine Phosphatase Detection Using Chemical Probes (2011)

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[56]-Development of PNA-array platforms for detection of genetic polymorphism of cytochrome p450 2c19. (2011)

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[55]-Modulation of exosome-mediated mRNA turnover by interaction of GTP-binding protein 1 (GTPBP1) with its target mRNAs (2011)

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[54]-Photoreversible cellular imaging using photochrome-conjugated fullerene silica nanoparticles. (2011) 

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[53]-Brief report: L1 cell adhesion molecule, a novel surface molecule of human embryonic stem cells, is essential for self-renewal and pluripotency (2011)

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[52]-Large-scale expression in Escherichia coli and efficient purification of precursor and active caspase-7 by introduction of thrombin cleavage sites (2010)

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[51]-Enhanced immobilization of hexa-arginine-tagged esterase on gold nanoparticles using mixed self-assembled monolayers (2010)

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[50]-Crystal structure of ED-Eya2: insight into dual roles as a protein tyrosine phosphatase and a transcription factor (2010)

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[49]-Efficient selection of IgG Fc domain-binding peptides fused to fluorescent protein using E. coli Expression system and dot-blotting assay (2010)

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[48]-Annexin A4 interacts with the NF-kappaB p50 subunit and modulates NF-kappaB transcriptional activity in a Ca(2+)-dependent manner (2010)

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[47]-Proteomic analysis of pancreata from mini-pigs treated with streptozotocin as a type I diabetes models (2010)

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[46]-Real-time colorimetric screening of endopeptidase inhibitors using adenosine triphosphate (ATP)-stabilized gold nanoparticles (2010)

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[45]-An iminocoumarin-based fluorescent probe for the selective detection of dual-specific protein tyrosine phosphatases (2010)

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[44]-Development of a nanoparticle-based FRET sensor for ultrasensitive detection of phytoestrogen compounds (2010)

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[43]-Proteomic analysis of oxidative stress-induced neuronal cell death by using two-dimensional fluorescence difference gel electrophoresis (2010)

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[42]-An ISFET biosensor for the monitoring of maltose-induced conformational changes in MBP (2009)

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[41]-Simultaneous intracellular delivery of targeting antibodies and functional nanoparticles with engineered protein G system (2009)

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[40]-VDUP1 potentiates Ras-mediated angiogenesis via ROS production in endothelial cells (2009)

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[39]-Far upstream element-binding protein-1, a novel caspase substrate, acts as a cross-talker between apoptosis and the c-myc oncogene (2009)

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[38]-An operationally simple colorimetric assay of hyaluronidase activity using cationic gold nanoparticles (2009)

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[37]-Monitoring of Cleavage Preference for Caspase-3 Using Recombinant Protein Substrates (2009)

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[36]-A highly selective fluorescent ESIPT probe for the dual specificity phosphatase MKP-6 (2009)

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[35]-Cascade enzyme-linked immunosorbent assay (CELISA) (2009)

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[34]-Glyceraldehyde-3-phosphate, a glycolytic intermediate, plays a key role in controlling cell fate via inhibition of caspase activity (2009)

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[33]-Synthesis and anticancer activity of geldanamycin derivatives derived from biosynthetically generated metabolites (2008)

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[32]-Characteristics of localized surface plasmon resonance of nanostructured Au patterns for biosensing (2008)

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[31]-Heparin-immobilized pluronic/PVA composite microparticles for the sustained delivery of ionic drug (2008)

[30]-Controlled antibody immobilization onto immunoanalytical platforms by synthetic peptide (2008)

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[29]-Directed immobilization of DNA-binding proteins on a cognate DNA-modified chip surface (2008)

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[28]-Structure of human alpha-enolase (hENO1), a multifunctional glycolytic enzyme (2008)

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[27]-Identification of proteins binding to decursinol by chemical proteomics (2008)

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[26]-Mixed self-assembly of polydiacetylenes for highly specific and sensitive strip biosensors (2008)

[25]-, A potent reporter applicable to the monitoring of caspase-3-dependent proteolytic cleavage (2008)

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[24]-Large scale preparation of active caspase-3 in e. coli by designing its thrombin-activatable precursors (2008)

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[23]-Stress-governed expression and purification of human type II hexokinase in Escherichia coli (2007)

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[22]-Reconstruction on the application category of pharmaceutical additives and boundaries of pharmaceutical additives according to the dosage forms (2007)

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[21]-Horseradish peroxidase (HRP) immobilized poly(aniline-co-m-aminophenol) film electrodes-fabrication and evaluation as a hydrogen peroxide sensor (2007)

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[20]-Verdine, Structure of human cytidine deaminase bound to a potent inhibitor (2005)

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[19]-A new imidazolium cavitand for the recognition of dicarboxylates (2004)

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[18]-Structures of end-products resulting from lesion processing by a DNA glycoylase/lyase (2004)

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[17]-Structural and biochemical exploration of a critical amino acid in human 8-oxoguanine glycosylase (2003)

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[16]-Insight into the stereochemistry in the inhibition of carboxypeptidase A with N-(hydroxyaminocarbonyl) phenylalanine: binding modes of an enantiomeric pair of the inhibitor to carboxypeptidase A (2002)

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[15]-Cleavage of beta-lactone ring by serine protease. Mechanistic implications (2002)

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[14]-N-(Hydroxyaminocarbonyl)phenylalanine: a novel class of inhibitor for carboxypeptidase A (2001)

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[13]-Mechanistic insight into the inactivation of carboxypeptidase a by ?-benzyl-2-oxo-1,3-oxazolidine-4-acetic acid, a novel type of irreversible inhibitor for carboxypeptidase a with no stereospecificity (2001)

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[12]-A novel strategy for designing irreversible inhibitors of metalloproteases: acetals as latent electrophiles that interact with catalytic nucleophile at the active site (2000)

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[11]-Selective inhibition of β-1,4- and α-1,3-galactosyltransferases: donor sugar nucleotide based approach (1999) 

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[10]-A novel type of structurally simple nonpeptide inhibitors for ?-chymotrypsin. Induced-fit binding of methyl 2-allyl-3-benzenepropanoate to the S2 subsite pocket (1998)

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[9]-Irreversible inhibition of zinc-containing protease by oxazolidinone derivatives. novel inactivation chemistry (1998)

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[8]-Acceptor substrate-based selective inhibition of galatosyltransferases (1998)

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[7]-Intramolecular edge-to-face aromatic-aromatic ring interactions in 3-(3-aryl-2-isopropylpropanoyl)-4-phenylmethyl-1,3-oxazolidin-2-ones prepared from evans chiral auxiliary (1997)

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[6]-Convenient Synthesis of 6-Substituted-2-chloro-5,12-dihydro-5-oxobenzoxazolo[3,2-a]quinolines and N-acylated-3-chlorodibenz[b,e][1,4] oxazepin-11(5H)-ones (1997)

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[5]-Synthesis and evaluation of 3-fluoro-2-piperazinyl-5,8,13-trihydro-5-oxoquino[1,2-a][3,1]benzoxazine-6-carboxylic acids as potential antibacterial agents (1996)

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[4]-Use of heteroatom containing small cyclic compounds for enzyme inhibitor design (1996)

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[3]-Inactivation of carboxypeptidase A by 2-benzyl-3,4-epithiobutanoic acid (1995)

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[2]-3-Fluoro-2-(4-methylpiperazin-1-yl)-5,12-dihydro-5-oxobenzoxazolo[3,2-a]quinoline-6-carboxylic acid: synthesis and in vitro cytotoxic activity (1995)

[1]-Synthesis of 3-fluoro-2-substituted-amino-5,12-dihydro-5-oxobenzoxazolo[3,2-a]quinoline-6-carboxylic acids employing the tandem double ring closure reaction of N-acetyl-N-(2’-hydroxyphenyl)anthranilic acid as the key step (1995)