PUBLISHED WORK

[96]-Biogenic nanomaterials: Synthesis, characterization, growth mechanism, and biomedical applications (2019)

[95]-Ginkgetin, a biflavone from Ginkgo biloba leaves, prevents adipogenesis through STAT5-mediated PPARγ and C/EBPα regulation (2019)

[94]-Monitoring metal-amyloid-β complexation by a FRET-based probe: design, detection, and inhibitor screening (2019)

[93]-Sesquiterpenes from Curcuma zedoaria rhizomes and their cytotoxicity against human gastric cancer AGS cells (2019)

[92]-Fridamycin A, a Microbial Natural Product, Stimulates Glucose Uptake without Inducing Adipogenesis (2019)

[91]-Identification of chebulinic acid as a dual targeting inhibitor of protein tyrosine phosphatases relevant to insulin resistance (2019)

[90]-Metal-induced redshift of optical spectra of gold nanoparticles: An instant, sensitive, and selective visual detection of lead ions (2019)

[89]-Recent Advances in pH-Sensitive Polymeric Nanoparticles for Smart Drug Delivery in Cancer Therapy (2018) 

[88]-Ginkgolic acid as a dual-targeting inhibitor for protein tyrosine phosphatases relevant to insulin resistance, Bioorganic Chemistry (2018) 

[87]-Label-free detection of protein tyrosine phosphatase 1B (PTP1B) using a rationally designed Forster resonance energy transfer (FRET) probe (2018) 

[86]-Identification of sennoside A as a novel inhibitor of the slingshot (SSH) family proteins related to cancer metastasis (2017) 

[85]-Intrinsic Forster resonance energy transfer imaging technique (iFIT) for detection of native protein in live cells (2016) 

[84]-Mitochondria-Targeting Chromogenic and Fluorescence Turn-On Probe for the Selective Detection of Cysteine by Caged Oxazolidinoindocyanine (2016) 

[83]-Cyclic peptide ligand with high binding capacity for affinity purification of immunoglobulin G (2016) 

[82]-Development of Stable Non-Ionic Lipid Nanoparticles (2016) 

[81]-Fc-binding ligands of immunoglobulin G: An overview of high affinity proteins and peptides (2016) 

[80]-Homogeneous detection of caspase-3 using intrinsic fluorescence resonance energy transfer (iFRET) (2015) 

[79]-Stimulation of angiogenesis and survival of endothelial cells by human monoclonal Tie2 receptor antibody (2015) 

[78]-A lactate-induced response to hypoxia (2015) 

[77]-IgG Fc-Binding Peptide (FcBP)-Tat Conjugate as a Smart Antibody Carrier into Live Cells (2015) 

[76]-Phosphoprotein phosphatase 1CB (PPP1CB), a novel adipogenic activator, promotes 3T3-L1 adipogenesis (2015) 

[75]-Functionalized Protein Nanocages as a Platform of Targeted Therapy and Immunodetection (2015) 

[74]-Discovery of coumarin derivatives as acceptors for intrinsic fluorescence resonance energy transfer (iFRET) of proteins (2014) 

[73]-ToF-SIMS analysis of diadenosine triphosphate and didadenosine tetraphosphate using bismuth and argon cluster ion beams (2014) 

[72]-Intrinsic tryptophan fluorescence in the detection and analysis of proteins: a focus on Forster resonance energy transfer techniques (2014) 

[71]-Structural basis for the dephosphorylating activity of PTPRQ towards phosphatidylinositide substrates (2013)

[70]-Recent Advances in Target Characterization and Identification by Photoaffinity Probes (2013)

[69]-Structural asymmetry of procaspase-7 bound to a specific inhibitor (2013)

[68]-Chitosan-based intelligent theragnosis nanocomposites enable pH-sensitive drug release with MR-guided imaging for cancer therapy (2013) 

[67]-Fabrication of nanoporous TiO2 hollow capsules using core-shell silica nanoparticle templates (2012)

[66]-Glyceraldehyde-3-phosphate, a glycolytic intermediate, prevents cells from apoptosis by lowering s-nitrosylation of glyceraldehyde-3-phosphate dehydrogenase (2012)

[65]-Identification of 3-acyl-2-phenylamino-1,4-dihydroquinolin-4-one derivatives as inhibitors of the phosphatase SerB653 in Porphyromonas gingivalis, implicated in periodontitis (2012)

[64]-Color-Tunable Photoluminescent Fullerene Nanoparticles (2012)

[63]-Molecular insight into the role of the leucine residue on the L2 loop in the catalytic activity of caspase-3 and -7 (2012)

[62]-Developing an antibody-binding protein cage as a modular delivery nanoplatform (2012)

[61]-A selective seoul-fluor-based bioprobe, sfbp, for vaccinia h1-related phosphatase?a dual-specific protein tyrosine phosphatase (2012)

[60]-Acetylation of malate dehydrogenase 1 promotes adipogenic differentiation via activating its enzymatic activity (2012)

[59]-Crystal structure of xenotropic murine leukaemia virus-related virus (XMRV) ribonuclease H (2012)

[58]-A facile synthetic route to diazepinone derivatives via ring closing metathesis and its application for human cytidine deaminase inhibitors (2012)

[57]-Recent Advances in Protein Tyrosine Phosphatase Detection Using Chemical Probes (2011)

[56]-Development of PNA-array platforms for detection of genetic polymorphism of cytochrome p450 2c19. (2011)

[55]-Modulation of exosome-mediated mRNA turnover by interaction of GTP-binding protein 1 (GTPBP1) with its target mRNAs (2011)

[54]-Photoreversible cellular imaging using photochrome-conjugated fullerene silica nanoparticles. (2011) 

[53]-Brief report: L1 cell adhesion molecule, a novel surface molecule of human embryonic stem cells, is essential for self-renewal and pluripotency (2011)

[52]-Large-scale expression in Escherichia coli and efficient purification of precursor and active caspase-7 by introduction of thrombin cleavage sites (2010)

[51]-Enhanced immobilization of hexa-arginine-tagged esterase on gold nanoparticles using mixed self-assembled monolayers (2010)

[50]-Crystal structure of ED-Eya2: insight into dual roles as a protein tyrosine phosphatase and a transcription factor (2010)

[49]-Efficient selection of IgG Fc domain-binding peptides fused to fluorescent protein using E. coli Expression system and dot-blotting assay (2010)

[48]-Annexin A4 interacts with the NF-kappaB p50 subunit and modulates NF-kappaB transcriptional activity in a Ca(2+)-dependent manner (2010)

[47]-Proteomic analysis of pancreata from mini-pigs treated with streptozotocin as a type I diabetes models (2010)

[46]-Real-time colorimetric screening of endopeptidase inhibitors using adenosine triphosphate (ATP)-stabilized gold nanoparticles (2010)

[45]-An iminocoumarin-based fluorescent probe for the selective detection of dual-specific protein tyrosine phosphatases (2010)

[44]-Development of a nanoparticle-based FRET sensor for ultrasensitive detection of phytoestrogen compounds (2010)

[43]-Proteomic analysis of oxidative stress-induced neuronal cell death by using two-dimensional fluorescence difference gel electrophoresis (2010)

[42]-An ISFET biosensor for the monitoring of maltose-induced conformational changes in MBP (2009)

[41]-Simultaneous intracellular delivery of targeting antibodies and functional nanoparticles with engineered protein G system (2009)

[40]-VDUP1 potentiates Ras-mediated angiogenesis via ROS production in endothelial cells (2009)

[39]-Far upstream element-binding protein-1, a novel caspase substrate, acts as a cross-talker between apoptosis and the c-myc oncogene (2009)

[38]-An operationally simple colorimetric assay of hyaluronidase activity using cationic gold nanoparticles (2009)

[37]-Monitoring of Cleavage Preference for Caspase-3 Using Recombinant Protein Substrates (2009)

[36]-A highly selective fluorescent ESIPT probe for the dual specificity phosphatase MKP-6 (2009)

[35]-Cascade enzyme-linked immunosorbent assay (CELISA) (2009)

[34]-Glyceraldehyde-3-phosphate, a glycolytic intermediate, plays a key role in controlling cell fate via inhibition of caspase activity (2009)

[33]-Synthesis and anticancer activity of geldanamycin derivatives derived from biosynthetically generated metabolites (2008)

[32]-Characteristics of localized surface plasmon resonance of nanostructured Au patterns for biosensing (2008)

[31]-Heparin-immobilized pluronic/PVA composite microparticles for the sustained delivery of ionic drug (2008)


[30]-Controlled antibody immobilization onto immunoanalytical platforms by synthetic peptide (2008)

[29]-Directed immobilization of DNA-binding proteins on a cognate DNA-modified chip surface (2008)

[28]-Structure of human alpha-enolase (hENO1), a multifunctional glycolytic enzyme (2008)

[27]-Identification of proteins binding to decursinol by chemical proteomics (2008)

[26]-Mixed self-assembly of polydiacetylenes for highly specific and sensitive strip biosensors (2008)


[25]-, A potent reporter applicable to the monitoring of caspase-3-dependent proteolytic cleavage (2008)

[24]-Large scale preparation of active caspase-3 in e. coli by designing its thrombin-activatable precursors (2008)

[23]-Stress-governed expression and purification of human type II hexokinase in Escherichia coli (2007)

[22]-Reconstruction on the application category of pharmaceutical additives and boundaries of pharmaceutical additives according to the dosage forms (2007)

[21]-Horseradish peroxidase (HRP) immobilized poly(aniline-co-m-aminophenol) film electrodes-fabrication and evaluation as a hydrogen peroxide sensor (2007)

[20]-Verdine, Structure of human cytidine deaminase bound to a potent inhibitor (2005)

[19]-A new imidazolium cavitand for the recognition of dicarboxylates (2004)

[18]-Structures of end-products resulting from lesion processing by a DNA glycoylase/lyase (2004)

[17]-Structural and biochemical exploration of a critical amino acid in human 8-oxoguanine glycosylase (2003)

[16]-Insight into the stereochemistry in the inhibition of carboxypeptidase A with N-(hydroxyaminocarbonyl) phenylalanine: binding modes of an enantiomeric pair of the inhibitor to carboxypeptidase A (2002)

[15]-Cleavage of beta-lactone ring by serine protease. Mechanistic implications (2002)

[14]-N-(Hydroxyaminocarbonyl)phenylalanine: a novel class of inhibitor for carboxypeptidase A (2001)

[13]-Mechanistic insight into the inactivation of carboxypeptidase a by ?-benzyl-2-oxo-1,3-oxazolidine-4-acetic acid, a novel type of irreversible inhibitor for carboxypeptidase a with no stereospecificity (2001)

[12]-A novel strategy for designing irreversible inhibitors of metalloproteases: acetals as latent electrophiles that interact with catalytic nucleophile at the active site (2000)

[11]-Selective inhibition of β-1,4- and α-1,3-galactosyltransferases: donor sugar nucleotide based approach (1999) 

[10]-A novel type of structurally simple nonpeptide inhibitors for ?-chymotrypsin. Induced-fit binding of methyl 2-allyl-3-benzenepropanoate to the S2 subsite pocket (1998)

[9]-Irreversible inhibition of zinc-containing protease by oxazolidinone derivatives. novel inactivation chemistry (1998)

[8]-Acceptor substrate-based selective inhibition of galatosyltransferases (1998)

[7]-Intramolecular edge-to-face aromatic-aromatic ring interactions in 3-(3-aryl-2-isopropylpropanoyl)-4-phenylmethyl-1,3-oxazolidin-2-ones prepared from evans chiral auxiliary (1997)

[6]-Convenient Synthesis of 6-Substituted-2-chloro-5,12-dihydro-5-oxobenzoxazolo[3,2-a]quinolines and N-acylated-3-chlorodibenz[b,e][1,4] oxazepin-11(5H)-ones (1997)

[5]-Synthesis and evaluation of 3-fluoro-2-piperazinyl-5,8,13-trihydro-5-oxoquino[1,2-a][3,1]benzoxazine-6-carboxylic acids as potential antibacterial agents (1996)

[4]-Use of heteroatom containing small cyclic compounds for enzyme inhibitor design (1996)

[3]-Inactivation of carboxypeptidase A by 2-benzyl-3,4-epithiobutanoic acid (1995)

[2]-3-Fluoro-2-(4-methylpiperazin-1-yl)-5,12-dihydro-5-oxobenzoxazolo[3,2-a]quinoline-6-carboxylic acid: synthesis and in vitro cytotoxic activity (1995)


[1]-Synthesis of 3-fluoro-2-substituted-amino-5,12-dihydro-5-oxobenzoxazolo[3,2-a]quinoline-6-carboxylic acids employing the tandem double ring closure reaction of N-acetyl-N-(2’-hydroxyphenyl)anthranilic acid as the key step (1995)

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